China Hydrodynamic Penetration

Cite Download Share Embed. With continuously increasing computational power, a numerical approach gradually becomes more prominent combined with experimental and theoretical methods in investigations of performance of a shaped-charge jet and its target penetration. This paper presents a meshfree methodology - Smoothed Particle Hydrodynamics SPH - for a shaped charge penetrating underwater structures. First, a SPH model of a sphere impacting a plate is developed; its numerical results agree well with the experimental data, verifying the validity of the mentioned developed method.
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Study on Hydrodynamic and Erosion-Deposition Change after Artificial Islands Construction

Current nanomedicine suffers from a big challenge due to the fact that most of the nanocarrier systems lack the desired tumor penetration depth, thereby limiting their clinical translation. Unlike the nanomaterials with a similar size or shape, microgels display excellent softness, fluidity and deformability, as well as stimuli-responsiveness in the tumor microenvironment. The prepared microgels were well characterized with different techniques. We show that regardless of the size, crosslinking density, MEA content and OEGA chain length, all microgels display the desired cytocompatibility in the given concentration range. In vitro cellular uptake data reveal that similar to 2-dimensional 2-D adherent cells, microgels with a smaller size display more enhanced cellular uptake than those having a larger size in the 3-D MCTS model.
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The size effect of mesoporous organosilica nanoparticles MONs on tumor penetration and accumulation remains poorly understood, which strongly affects the tumor therapeutic efficacy. Herein, four different-sized thioether-bridged MONs 20, 40, 60, and nm are synthesized; all the MONs have a spherical morphology, excellent dispersity, similar surface charge, uniform mesopores 3. In vivo experiments show that the 40 nm MONs possess the longest mean residence times, leading to their highest accumulation in blood and tumors.
Science China Technological Sciences. The modified hydrodynamic theory of long rod penetration into semi-infinite targets was established independently by Alekseevskii and Tate over forty years ago and since then many investigators contributed much to the development of the high speed penetration mechanics. However, in all the models proposed so far, the target resistance R t is not well defined and usually determined by adjusting it until the predicted depth of penetration comes to an agreement with experimental data.
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